基础医学(学术型)

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张聪(基础医学院)

信息来源:沈江恩 发布日期:2026-03-10 点击量:

张聪,医学博士,副教授,硕士研究生导师,中华中医药学会中药实验药理分会青年委员,《巴楚医学》杂志青年编委。长期从事代谢紊乱相关疾病发生机制及药物防治研究,主持国家自然科学基金项目1项、湖北省自然科学基金项目2项及其他纵向科研项目7项;以第一作者或通讯作者在Advanced Science、Phytomedicine、Journal of Agricultural and Food Chemistry、Free Radical Biology and Medicine等期刊发表SCI论文20余篇,其中湖北省科协优秀科技论文1篇,并荣获Wiley中国高贡献作者奖。

主要研究方向:代谢紊乱相关疾病(肝病/肾病)发生机制与药物防治

招生方向:基础医学(学术型)、临床医学(学术型)

联系方式:zzzcyyc520@126.com; zhangcong@ctgu.edu.cn

近三年主要研究成果:

1. Cong Zhang, Yu Guo, Yi Liu, et al. Sperm miR-142-3p reprogramming mediates paternal pre-pregnancy caffeine exposure-induced non-alcoholic steatohepatitis in male offspring rats. Advanced Science, 2024: 2405592.(中科院1区Top,IF 14.3,共同第一作者)

2. Cong Zhang, Qiao Tong, Kexin Liu, et al. Morroniside delays the progression of non-alcoholic steatohepatitis by promoting AMPK-mediated lipophagy. Phytomedicine, 2024: 155703.(中科院1区Top,IF 8.3,第一作者&共同通讯作者)

3. Cong Zhang, Yingxi Luo, Yangkun Xiong, et al. Gigantol ameliorates metabolic dysfunction-associated steatohepatitis by promoting TFEB-mediated lipophagy and fatty acid oxidation. Journal of Agricultural and Food Chemistry, 2026, 74, 5, 4389-4406.(中科院1区Top,IF 6.2,第一作者&共同通讯作者)

4. Cong Zhang, Yangkun Xiong, Mingyang Gong, et al. Pachymic acid ameliorates fructose-driven hyperuricemic nephropathy in mice by suppressing ferroptosis via activating Nrf2/GPX-4 pathway. Journal of Agricultural and Food Chemistry, 2025, 73.36: 22778-22793.(中科院1区Top,IF 6.2,第一作者&共同通讯作者)

5. Cong Zhang, Yangkun Xiong, Yingxi Luo, et al. Morroniside ameliorates high-fat and high-fructose-driven chronic kidney disease by motivating AMPK-TFEB signal activation to accelerate lipophagy and inhibiting inflammatory response. Journal of Agricultural and Food Chemistry, 2025, 73(10), 6158-6172.(中科院1区Top,IF 6.2,第一作者&共同通讯作者)

6. Ye Cheng, Zhengjie Lu, Tongyun Mao, et al. Magnoflorine ameliorates chronic kidney disease in high-fat and high-fructose-fed mice by promoting Parkin/PINK1-dependent mitophagy to inhibit NLRP3/Caspase-1-mediated pyroptosis. Journal of Agricultural and Food Chemistry, 2024, 3c09634.(中科院1区Top,IF 6.2,共同通讯作者)

7. Cong Zhang, Yingying Song, Ming Yuan, et al. Ellagitannins-derived intestinal microbial metabolite urolithin A ameliorates fructose-driven hepatosteatosis by suppressing hepatic lipid metabolic reprogramming and inducing lipophagy. Journal of Agricultural and Food Chemistry, 2023, 3967-3980.(中科院1区Top,IF 6.2,共同第一作者)

8. Cong Zhang, Dingmei Zhang, Hegui Huang, et al. Cathepsin D mediates prenatal caffeine exposure-caused NAFLD susceptibility in male rat offspring by regulating autophagy. Free Radical Biology and Medicine, 2023, 208: 684-699.(中科院2区Top, IF 8.2,共同第一作者)

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